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Also, it is known to have a significant role in producing the immune response and contributing to the pathogenesis of immense diseases such as rheumatoid arthritis

In addition, the benchmarking approach provides an alternative to the traditional validation of NAMS against apical effects in rodent studies but rather tries to evaluate the NAMs in the context of making protective safety decisions ( in vitro culture methodologies (van der Zalm et al., 2022)

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